מסגרת עם רקע לכותרת

Anti–Vascular Endothelial Growth Factor Therapy Can Improve Diabetic Retinopathy Score Without Change in Retinal Perfusion

תמונת נושא מאמר
18.03.2019 | Bonnin, Sophie MD; Dupas, Bénédicte MD; Lavia, Carlo MD,†; Erginay, Ali MD; Dhundass, Myriam MD; Couturier, Aude MD; Gaudric, Alain MD; Tadayoni, Ramin MD, PhD

Purpose:

To compare the changes in retinal perfusion on ultra–wide-field fluorescein angiography with the changes in diabetic retinopathy lesions observed on ultra–wide-field fundus color photographs after 3 monthly anti–vascular endothelial growth factor injections.

 

Methods:

 Retrospective interventional cohort study analyzing the files of 14 patients with DR (18 eyes). UWF color photos and FA were analyzed at baseline (M0) and 1 month after the third anti-VEGF injection (M3).

 

The main outcomes included the count of the number of red dots (microaneurysms, hemorrhages) and assessment of DR severity score (DRSS); the analysis of non-perfusion areas and disappearance or reappearance of arterioles or venules in the non-perfusion areas on FA.

 

Retina 39(3):p 426-434, March 2019. | DOI: 10.1097/IAE.0000000000002422
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