Are the polypoidal lesions in patients with polypoidal choroidal vasculopathy identified as aneurysmal dilatations or neovascularization on swept-source optical coherence tomographic angiography?

Findings  In this cross-sectional study of 23 eyes from 20 patients with polypoidal choroidal vasculopathy, all 43 polypoidal lesions identified using indocyanine green angiography appeared as tangled new vessels on swept-source optical coherence tomographic angiography rather than aneurysmal lesions.

Meaning  The identification of polypoidal lesions in patients with polypoidal choroidal vasculopathy as neovascular tangles rather than actual polypoidal lesions or aneurysmal dilatations may help facilitate understanding of their pathogenesis and response to treatment.