Eye cancer staging systems used for standardizing patient care and research need to be validated.

evaluate the accuracy of the eighth edition of the American Joint Committee on Cancer (AJCC) Cancer Staging Manual in estimating metastatis and

mortality rates of conjunctival melanoma.

This international, multicenter, registry-based case series pooled data from 10 ophthalmic oncology centers from 9 countries on 4 continents. A total of 288 patients diagnosed with conjunctival melanoma from January 1, 2001, to December 31, 2013, were studied.

Data analysis was performed from July 7, 2018, to September 11, 2018.

included excision biopsy, cryotherapy, topical chemotherapy, radiation therapy, enucleation, and exenteration.