בשל "הגנת זכויות יוצרים", מובא להלן קישור למאמר בלבד. לקריאתו בטקסט מלא, אנא פנה לספרייה הרפואית הזמינה לך.

To investigate predictive factors associated with the rate of visual field (VF) loss in open-angle glaucoma.

Perimetric glaucoma patients of the Advanced Imaging for Glaucoma study were selected for analysis if they had 9 completed visits.

Confirmed rapid significant progression (CRSP) of VF was defined as a significant (P < 0.05) negative VF index (VFI) slope of −1%/year or a mean deviation slope of −0.5 dB/year, confirmed at 2 consecutive follow-up visits.

Slow progression was defined as VFI slope greater than −0.5%/year or a mean deviation slope of −0.25 dB/year.

Fourier-domain optical coherence tomography (FD-OCT) measured optic disc, peripapillary retinal nerve fiber layer (NFL), and macular ganglion cell complex (GCC) thicknesses.

Logistic regression was used to identify baseline predictors for CRSP and slow progression. Linear regression was used to identify baseline predictors for the VFI and mean deviation slope.

Conclusions

Focal loss measured by FD-OCT or VF along with CCT are strong baseline predictors for the rate of glaucoma progression.